Dr. Vivek Nambiar

Dr. Vivek Nambiar

Clinical Associate Professor
MD (Internal Medicine), DM (Neurology), Fellowship in Vascular Neurology and Stroke (Calgary, Canada)
Speciality: Stroke Medicine
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Experience
Stroke Research – At University of Calgary
Affiliations to Organizations
Presentations

Training & Work Experience

  • Assistant Professor of Neurology and Head of Division of Stroke, Amrita Institute of Medical Sciences, Kochi from August 2013 onwards
  • Stroke Fellowship, Calgary, Canada - 2011- 2013
  • Consultant Neurologist, Caritas Hospital, Kottayam – 2009 – 2011
  • Research Officer, Neuro epidemiology, Bombay Hospital - 01/06/2009 - 30/06/2009
  • Senior Registrar in Neurology - 2006–2009
  • DM Neurology under Professor Nadir E. Bharucha, Bombay Hospital Institute of Medical Sciences, Mumbai, India - Clinical decision making, regular-in patient management, teaching internal medicine and pediatrics post graduate residents, Electrophysiology, acute stroke therapeutics involving thrombolytic treatment.
  • Worked with Dr. Anil Karapurkar, neuro-inteventionalist 2007, Bombay Hospital attended carotid stenting, AVM, aneurysm management
  • Prof. K.Radhakrishnan, Sri Chitra Tirunal Institute, 2008 Kerala, India. - Electrophysiology training

 

Post M.D. Experience

  • Assistant Professor (Medicine) Jan – Jun 2006 Karuna Medical College, Palghat, Kerala, India - Teaching UG students & managing medical wards
  • In charge, Dept. of Cardiology 2004 – 2005 MOSSC Mission Hospital Trichur, Kerala - Management of cardiac emergencies, thrombolysis,ventilatory care

 

Research Experience

Ongoing projects:

  • Director, province-wide Telestroke program, by Govt of Kerala state
  • Principal Research Co-ordinator, Kerala State Prospective Stroke Registry, by Kerala Association of Neurologists
  • Local PI, ATTEND trial ( a prospective randomzed trial on home-based physiotherapy in India)
  • Local PI, Maternal and neonatal stroke registry by University of North Carolina
  • Ongoing prospective studies on
    • Isoprostenoids and Aspirin resistance in acute stroke
    • TORBSST evaluation in acute stroke patients
    • Anticoagulation in Episodic atrial tachycardia
    • A two year experience of carotid stenting
    • Amyloid angiopathy in TIA and stroke

Certifications of GCP, various stroke scales -NIHSS, ASPECTS, Stata12.2 course( statistical software training)
Actively involved as sub investigator in the following trials

  • INTERSeCT study - Imaging study on clot features in acute stroke ( Multi centric observational study)
  • ALIAS study - Randomized Trial on Albumin and placebo in acute moderate to severe ischemic stroke)
  • DOUBT study- TIA like episodes prospective study
  • IMS-3 study-Interventional management of stroke –RCT on endovascular or intravenous tPA trial
  • CATCH study- Prospective observational study on effect of sleep apnea in minor stroke and TIA
  • ASPIRE study- TIA related community study
  • RESPECT study- Patent foramen ovale closure in embolic stroke – Multi centric RCT
  • PROVE-IT study- Perfusion CT or CT angiography in acute stroke
  • AQUT study-Acute qualitative T2 image study of reperfusion injury in acute stroke
  • STOP-IT – study of Factor 7 on ICH
  • SPOTLIGHT- of factor seven or placebo RCT in ICH
  • GLORIA Registry-Safety registry for Dabigatran
  • STAR registry- Solitaire stent retrieval in acute stroke
  • ESCAPE- Randomised trial of endovascular stent retrieval and iv tPA in acute strokes within 12 hours.

Co investigator in

  • Near infra red spectroscopy in Acute ischemic stroke study.
  • Research Officer August 2009 - Department of Neuroepidemiology and Neurology, Bombay Hospital, Mumbai, India
  • Co-investigator 2003-2004 - Leptospirosis Project, State Medical Research Council, Kerala, India
  • Association of Physicians, India
  • Bombay Academy of Neurosciences
  • Maharashtra Association of Neurology
  • Indian Academy of Neurology
  • Neurological Society of India
  • World Stroke Organization
  • Indian Stroke Association
  • Asymptomatic carotid stenosis- Is medical management sufficient’ as invited speaker at Indian Stroke Association Annual conference 2014, Trivandrum.
  • Do reduced leptomeningeal collaterals in humans result in leukoaraiosis, lacunes and brain atrophy? Vivek Nambiar, Ondrej Volny, Sung Il Sohn, Emmad Qazi, Jayme Kosior, Mayank Goyal, Andrew M Demchuk, Bijoy K Menon. Europian stroke conference London 2013.
  • Do baseline infarct volume thresholds predict outcome in acute ischemic stroke depending on how fast recanalization achieved? Vivek Nambiar, Sung Il Sohn, Emmad Qazi, Jayme Kosior, Mayank Goyal, Andrew M Demchuk, Bijoy K Menon-Platform presentation,European Stroke Conference , Lisbon May 2012.
  • Lepto meningeal collaterals; Role in infarct growth reduction in patients with acute ischemic stroke Vivek Nambiar, Sung Il Sohn, Emmad Qazi, Abdul Qazi, Jayme Kosior, Mayank Goyal, Michael D Hill,Andrew M Demchuk, Bijoy K Menon CSC,2012
  • Can attenuation characteristics on NCCT can be used instead the diffusion FLAIR mismatch in imaging triage of acute ischemic stroke patients? Vivek Nambiar, SI Sohn, E Qazi, A Qazi,J Kosior, M Goyal, MD Hill,AM Demchuk, BK Menon .Canadian Stroke Congress, Calgary, Canada 2012.
  • Malignant emboli detected by TCD monitoring may predict post procedural DWI lesions and is most common during stent and distal protection device deployment during CAS. Mohammed A Almekhlafi, MD, MSc, FRCPC; Sachin Mishra, MD; Vivek Nambiar, DM, MD,Mayank Goyal, MD, FRCPC; Andrew M Demchuk,MD,FRCPC American Heart Association, Honolulu 2013.
  • Qualitative or quantitative flair changes on MRI brain in acute ischemic strokes with major proximal occlusions does not predict intracranial hemorrhages S Adatia, V Nambiar, M Almekhlafi, SI Sohn, BK Menon, A Demchuk. Europian Neurological Soceity, Barcelona 2013.
  • Not All Successful Reperfusion Patients Are Equal: The Need for a TICI2c Score. Mohammed A Almekhlafi, MD, MSc, FRCPC; Jamsheed Desai MD FRCPC; Sachin Mishra, MD; Vivek Nambiar, DM, MD; Muneer Eesa, MD; Bijoy K Menon, MD ; Ondrej Volny; Mayank Goyal, MD, FRCPC; Andrew M Demchuk, MD, FRCPC. ESC London 2013.
  • Octogenarians should not be excluded from acute stroke intervention trials as major clinical responses arecommon with reperfusion. Mohammed A Almekhlafi, MD, MSc, FRCPC; Sachin Mishra, MD; Vivek Nambiar, DM, MD; Jamsheed Desai MD,FRCPC; Muneer Eesa, MD; Bijoy K Menon, MD; Ondrej Volny; Mayank Goyal, MD, FRCPC; Andrew M Demchuk, MD, FRCPC. ESC London 2013.
  • Imaging-to- Stent deployment Time Interval Is Shorter during Daytime hours Vs. Evening Times in Endovascular Therapy for Acute Ischemic Stroke. Mohammed A Almekhlafi, MD, MSc, FRCPC, Jamsheed Desai MD FRCPC,Sachin Mishra, MD; Vivek Nambiar, DM, MD; Muneer Eesa, MD ; Bijoy K Menon, MD ; Ondrej Volny; Mayank Goyal, MD, FRCPC; Andrew M Demchuk, MD, FRCPC ESC London,2013 Accepted
  • Radiographic predictors of Major neurologic improvement after Mechanical thrombectomy assisted recanalization in acute stroke. Jamsheed Desai MD FRCPC, Mohammed A Almekhlafi, MD, MSc, FRCPC, Sachin Mishra, MD; Vivek Nambiar, DM, MD; Muneer Eesa, MD ; Bijoy K Menon, MD ; Ondrej Volny; Mayank Goyal, MD, FRCPC; Andrew M Demchuk, MD, FRCPC ESC London 2013 Accepted
  • Baseline clinical predictors of rapid neurological improvements in acute ishemic stroke patients treated with stentrievers. Jamsheed Desai MD FRCPC, Mohammed A Almekhlafi, MD, MSc, FRCPC; Vivek Nambiar, DM, MD; , Sachin Mishra, MD,Muneer Eesa, MD ; Bijoy K Menon, MD ; Ondrej Volny; Mayank Goyal, MD, FRCPC1; Andrew M Demchuk, MD, FRCPC ESC London 2013 Accepted
  • Achieving an IV Needle to Arterial Puncture Time under 60 Minutes in Acute Endovascular Stroke Therapy is Feasible. Jamsheed Desai MD FRCPC; Mohammed A Almekhlafi, MD, MSc, FRCPC; Vivek Nambiar, DM, MD; , Sachin Mishra, MD Muneer Eesa, MD ; Bijoy K Menon, MD ; Ondrej Volny; Mayank Goyal, MD, FRCPC; Andrew M Demchuk, MD, FRCPC ESC 2013,London, Accepted
  • Moya moya disease a rare cause of stroke- a case series, Vivek Nambiar,Yogesh Sharma, Nadir Bharucha. World Congress of Neurology, Bangkok. 2009
  • Hansen’s disease: Uncommon presentation of a common disease,Vivek Nambiar,Yogesh Sharma, Nadir Bharucha. World Congress of Neurology, Bangkok 2009
  • Bharucha NE, Raven RH, Nambiar VK. Status Epilepticus in HIV & TB. Innsbruck’s colloquium, Vienna, Austria 2009
  • Primary progressive aphasia, Bombay Neurosciences Academy, 2008
  • Multiple organ dysfunction in leptospirosis, API, Kerala Chapter, 2004
  • Arrhythmia in leptospiral mycocarditis, API, Kerala Chapter, 2004

Training & Work Experience

  • Assistant Professor of Neurology and Head of Division of Stroke, Amrita Institute of Medical Sciences, Kochi from August 2013 onwards
  • Stroke Fellowship, Calgary, Canada - 2011- 2013
  • Consultant Neurologist, Caritas Hospital, Kottayam – 2009 – 2011
  • Research Officer, Neuro epidemiology, Bombay Hospital - 01/06/2009 - 30/06/2009
  • Senior Registrar in Neurology - 2006–2009
  • DM Neurology under Professor Nadir E. Bharucha, Bombay Hospital Institute of Medical Sciences, Mumbai, India - Clinical decision making, regular-in patient management, teaching internal medicine and pediatrics post graduate residents, Electrophysiology, acute stroke therapeutics involving thrombolytic treatment.
  • Worked with Dr. Anil Karapurkar, neuro-inteventionalist 2007, Bombay Hospital attended carotid stenting, AVM, aneurysm management
  • Prof. K.Radhakrishnan, Sri Chitra Tirunal Institute, 2008 Kerala, India. - Electrophysiology training

 

Post M.D. Experience

  • Assistant Professor (Medicine) Jan – Jun 2006 Karuna Medical College, Palghat, Kerala, India - Teaching UG students & managing medical wards
  • In charge, Dept. of Cardiology 2004 – 2005 MOSSC Mission Hospital Trichur, Kerala - Management of cardiac emergencies, thrombolysis,ventilatory care

 

Research Experience

Ongoing projects:

  • Director, province-wide Telestroke program, by Govt of Kerala state
  • Principal Research Co-ordinator, Kerala State Prospective Stroke Registry, by Kerala Association of Neurologists
  • Local PI, ATTEND trial ( a prospective randomzed trial on home-based physiotherapy in India)
  • Local PI, Maternal and neonatal stroke registry by University of North Carolina
  • Ongoing prospective studies on
    • Isoprostenoids and Aspirin resistance in acute stroke
    • TORBSST evaluation in acute stroke patients
    • Anticoagulation in Episodic atrial tachycardia
    • A two year experience of carotid stenting
    • Amyloid angiopathy in TIA and stroke

Certifications of GCP, various stroke scales -NIHSS, ASPECTS, Stata12.2 course( statistical software training)
Actively involved as sub investigator in the following trials

  • INTERSeCT study - Imaging study on clot features in acute stroke ( Multi centric observational study)
  • ALIAS study - Randomized Trial on Albumin and placebo in acute moderate to severe ischemic stroke)
  • DOUBT study- TIA like episodes prospective study
  • IMS-3 study-Interventional management of stroke –RCT on endovascular or intravenous tPA trial
  • CATCH study- Prospective observational study on effect of sleep apnea in minor stroke and TIA
  • ASPIRE study- TIA related community study
  • RESPECT study- Patent foramen ovale closure in embolic stroke – Multi centric RCT
  • PROVE-IT study- Perfusion CT or CT angiography in acute stroke
  • AQUT study-Acute qualitative T2 image study of reperfusion injury in acute stroke
  • STOP-IT – study of Factor 7 on ICH
  • SPOTLIGHT- of factor seven or placebo RCT in ICH
  • GLORIA Registry-Safety registry for Dabigatran
  • STAR registry- Solitaire stent retrieval in acute stroke
  • ESCAPE- Randomised trial of endovascular stent retrieval and iv tPA in acute strokes within 12 hours.

Co investigator in

  • Near infra red spectroscopy in Acute ischemic stroke study.
  • Research Officer August 2009 - Department of Neuroepidemiology and Neurology, Bombay Hospital, Mumbai, India
  • Co-investigator 2003-2004 - Leptospirosis Project, State Medical Research Council, Kerala, India

  • Association of Physicians, India
  • Bombay Academy of Neurosciences
  • Maharashtra Association of Neurology
  • Indian Academy of Neurology
  • Neurological Society of India
  • World Stroke Organization
  • Indian Stroke Association

  • Asymptomatic carotid stenosis- Is medical management sufficient’ as invited speaker at Indian Stroke Association Annual conference 2014, Trivandrum.
  • Do reduced leptomeningeal collaterals in humans result in leukoaraiosis, lacunes and brain atrophy? Vivek Nambiar, Ondrej Volny, Sung Il Sohn, Emmad Qazi, Jayme Kosior, Mayank Goyal, Andrew M Demchuk, Bijoy K Menon. Europian stroke conference London 2013.
  • Do baseline infarct volume thresholds predict outcome in acute ischemic stroke depending on how fast recanalization achieved? Vivek Nambiar, Sung Il Sohn, Emmad Qazi, Jayme Kosior, Mayank Goyal, Andrew M Demchuk, Bijoy K Menon-Platform presentation,European Stroke Conference , Lisbon May 2012.
  • Lepto meningeal collaterals; Role in infarct growth reduction in patients with acute ischemic stroke Vivek Nambiar, Sung Il Sohn, Emmad Qazi, Abdul Qazi, Jayme Kosior, Mayank Goyal, Michael D Hill,Andrew M Demchuk, Bijoy K Menon CSC,2012
  • Can attenuation characteristics on NCCT can be used instead the diffusion FLAIR mismatch in imaging triage of acute ischemic stroke patients? Vivek Nambiar, SI Sohn, E Qazi, A Qazi,J Kosior, M Goyal, MD Hill,AM Demchuk, BK Menon .Canadian Stroke Congress, Calgary, Canada 2012.
  • Malignant emboli detected by TCD monitoring may predict post procedural DWI lesions and is most common during stent and distal protection device deployment during CAS. Mohammed A Almekhlafi, MD, MSc, FRCPC; Sachin Mishra, MD; Vivek Nambiar, DM, MD,Mayank Goyal, MD, FRCPC; Andrew M Demchuk,MD,FRCPC American Heart Association, Honolulu 2013.
  • Qualitative or quantitative flair changes on MRI brain in acute ischemic strokes with major proximal occlusions does not predict intracranial hemorrhages S Adatia, V Nambiar, M Almekhlafi, SI Sohn, BK Menon, A Demchuk. Europian Neurological Soceity, Barcelona 2013.
  • Not All Successful Reperfusion Patients Are Equal: The Need for a TICI2c Score. Mohammed A Almekhlafi, MD, MSc, FRCPC; Jamsheed Desai MD FRCPC; Sachin Mishra, MD; Vivek Nambiar, DM, MD; Muneer Eesa, MD; Bijoy K Menon, MD ; Ondrej Volny; Mayank Goyal, MD, FRCPC; Andrew M Demchuk, MD, FRCPC. ESC London 2013.
  • Octogenarians should not be excluded from acute stroke intervention trials as major clinical responses arecommon with reperfusion. Mohammed A Almekhlafi, MD, MSc, FRCPC; Sachin Mishra, MD; Vivek Nambiar, DM, MD; Jamsheed Desai MD,FRCPC; Muneer Eesa, MD; Bijoy K Menon, MD; Ondrej Volny; Mayank Goyal, MD, FRCPC; Andrew M Demchuk, MD, FRCPC. ESC London 2013.
  • Imaging-to- Stent deployment Time Interval Is Shorter during Daytime hours Vs. Evening Times in Endovascular Therapy for Acute Ischemic Stroke. Mohammed A Almekhlafi, MD, MSc, FRCPC, Jamsheed Desai MD FRCPC,Sachin Mishra, MD; Vivek Nambiar, DM, MD; Muneer Eesa, MD ; Bijoy K Menon, MD ; Ondrej Volny; Mayank Goyal, MD, FRCPC; Andrew M Demchuk, MD, FRCPC ESC London,2013 Accepted
  • Radiographic predictors of Major neurologic improvement after Mechanical thrombectomy assisted recanalization in acute stroke. Jamsheed Desai MD FRCPC, Mohammed A Almekhlafi, MD, MSc, FRCPC, Sachin Mishra, MD; Vivek Nambiar, DM, MD; Muneer Eesa, MD ; Bijoy K Menon, MD ; Ondrej Volny; Mayank Goyal, MD, FRCPC; Andrew M Demchuk, MD, FRCPC ESC London 2013 Accepted
  • Baseline clinical predictors of rapid neurological improvements in acute ishemic stroke patients treated with stentrievers. Jamsheed Desai MD FRCPC, Mohammed A Almekhlafi, MD, MSc, FRCPC; Vivek Nambiar, DM, MD; , Sachin Mishra, MD,Muneer Eesa, MD ; Bijoy K Menon, MD ; Ondrej Volny; Mayank Goyal, MD, FRCPC1; Andrew M Demchuk, MD, FRCPC ESC London 2013 Accepted
  • Achieving an IV Needle to Arterial Puncture Time under 60 Minutes in Acute Endovascular Stroke Therapy is Feasible. Jamsheed Desai MD FRCPC; Mohammed A Almekhlafi, MD, MSc, FRCPC; Vivek Nambiar, DM, MD; , Sachin Mishra, MD Muneer Eesa, MD ; Bijoy K Menon, MD ; Ondrej Volny; Mayank Goyal, MD, FRCPC; Andrew M Demchuk, MD, FRCPC ESC 2013,London, Accepted
  • Moya moya disease a rare cause of stroke- a case series, Vivek Nambiar,Yogesh Sharma, Nadir Bharucha. World Congress of Neurology, Bangkok. 2009
  • Hansen’s disease: Uncommon presentation of a common disease,Vivek Nambiar,Yogesh Sharma, Nadir Bharucha. World Congress of Neurology, Bangkok 2009
  • Bharucha NE, Raven RH, Nambiar VK. Status Epilepticus in HIV & TB. Innsbruck’s colloquium, Vienna, Austria 2009
  • Primary progressive aphasia, Bombay Neurosciences Academy, 2008
  • Multiple organ dysfunction in leptospirosis, API, Kerala Chapter, 2004
  • Arrhythmia in leptospiral mycocarditis, API, Kerala Chapter, 2004