Dr. S. Sudhindran

Dr. S. Sudhindran is the Clinical Professor and Chief Transplant Surgeon, Department of Gastrointestinal Surgery and Solid Organ Transplantation, Amrita Institute of Medical Sciences, Kochi. He is the first liver transplant surgeon in Kerala and a well-known expert in liver transplants. He has completed over 820 liver transplants, mostly live donor transplants. He also has expertise in pancreas transplant as well as small bowel transplants. He completed his MBBS and MS from Trivandrum Medical College. Later, he trained in vascular surgery and solid organ transplantation from the UK. He has worked as a Clinical Fellow in Transplantation in Addenbrooke’s Hospital, Cambridge. He has more than a hundred publications to his credit. He was awarded “The Distinguished Alumnus Award” by Trivandrum Medical College on February 15, 2020 in grateful appreciation for the leadership and outstanding service to the alma mater, Trivandrum Medical College and for the contributions to the society at large.

Previous Appointments :

Clinical Fellowship in Transplantation
Addenbrooke’s Hospital, Cambridge
April 2000 – September 2002

Specialist Registrar in Transplantation
Royal Liverpool University Hospital
October 1999 – April 2000

Specialist Registrar in Vascular Surgery
Royal Liverpool University Hospital.
October 1998 – September 1999

Specialist Registrar in Gen. & Vascular Surgery
Countess of Chester Hospital, Chester
October 1997 – September 1998

Specialist Registrar in Gen & Vascular Surgery
Aintree Hospitals NHS Trust
October 1996 – September 1997

Specialist Registrar in Surgery
Leighton hospital, Crewe, Cheshire
October 1995 – September 1996

Specialist Registrar in Surgery
Macclesfield District General Hospital
April 1995 – September 1995

SHO Surgery
Memorial Hospital, Darlington
August 1994 – March 1995

SHO A&E and Orthopaedics
Memorial Hospital, Darlington
February 1994 – August 1994

PRHO Surgery
Memorial Hospital, Darlington
August 1993 – January 1994

Registrar General Surgery and Gastroenterology
Devamatha Hospital, Kerala,
August 1991 – March 1993

SHO Rotation Surgery and allied specialties
Trivandrum Medical College, Kerala,
May 1988 – May 1991

PRHO (Surgery, Medicine, O&G, Paediatrics and Community Medicine)
Trivandrum Medical College, Kerala
April 1987 to April 1988

Publications:

Menon, R. N., Balakrishnan, D., Unnikrishnan, G., Saraf, V., Sudheer, O. V., Dhar, P., & Sudhindran, S. (2012, May). Hepatic Steatosis: Clinico-Pathological and Radiological Correlation Study as an Aid To Selecting Living Donor Grafts. Liver transplantation 2013 :18;S157-S158

Shemin, Z. K., Eapen, M., Jojo, A., Balakrishnan, D., Sudhindran S. Differing Aetiology of Acute Liver Failure in India, Compared to Other Countries. Liver transplantation  2013;19; S123-S123.

Ramamurthi, P., Nair, H. R., Sudhindran S. Predictors of ICU-Outcome and 3-Month Mortality in Living Donor Liver Transplant Recipients. Liver transplantation 2013 : 19;S274-S274).

Sudhindran S,  Menon RCN, Balakrishnan D. Challenges and Outcome of Left-lobe Liver Transplants in Adult Living Donor Liver Transplants. Journal of clinical and experimental hepatology 2012; 2(2):181-87.

Indu KN, Lakshminarayana G, Anil M, Rajesh R, George K, Ginil K, Georgy M, Nair B, Sudhindran S, Appu T, Unni VN, Sanjeevan KV. Is early removal of prophylactic ureteric stents beneficial in live donor renal transplantation? Indian J Nephrol. 2012 Jul;22(4):275-9.

Preetham H.S., Ismail Siyad K.H.. Harikumar R.Nair, Narayanan V.A., Sudhindran S. Correlation between postoperative liver function tests and short term (<1 year) mortality following living donor liver transplantation. Journal of Clinical & Experimental Hepatology, March 2013;3(1): S110-S111.

S Kalghatgi, S Vivek, U Dattaram, ST Binoj, P Nitin, M Ramachandran, G Unnikrishnan, B Dinesh, OV Sudheer, D Puneet, N Subhalal, S Sudhindran. Bilirubin as a predictor of early mortality after liver transplantation. Journal of clinical and experimental hepatology 2011;1(2):144-45.

Sudhindran S, Aboobacker S, Menon RN, Unnikrishnan G, Sudheer OV, Dhar P. Cost and efficacy of immunosuppression using generic products following living donor liver transplantation in India. Indian J Gastroenterol. 2012 Jan;31(1):20-3.

KumarA,   Sudhindran S,. Dinesh, KR, Vivek V, Karim S. Chromobacterium violaceum, A Rare Cause of Infected Pancreatic Pseudocyst Infect Dis Clin Pract March 2011;00: 00Y00

Kumar A, Augustine D, Sudhindran S, Kurian AM, Dinesh KR, Karim S, Philip Weissella confusa: a rare cause of vancomycin-resistant Gram-positive bacteraemia R.J Med Microbiol. 2011 Oct;60(Pt 10):1539-41.

Pavithran K, Sudhindran S. Hanging liver tumor. J Gastrointestin Liver Dis. 2011 Mar;20(1):8

Oral rivaroxaban for symptomatic venous thromboembolism. Einstein Investigators. NE.N Engl J Med. 2010 Dec 23;363(26):2499-510.

. A. Kumar, S. Sudhindran, V. Vivek, K. Dinesh, S. Karim.  Mycotic aneurysm due to Salmonella International Journal of Infectious Diseases Volume 14, Supplement 2 (July 2010) page S28 .

Chronic pancreatitis. A prospective nationwide study of 1,086 subjects from India. JOP. 2008 Sep 2;9(5):593-600.

A Phase 3, open-label, non-comparative study of tigecycline in the treatment of patients with selected serious infections due to resistant Gram-negative organisms including Enterobacter species, Acinetobacter baumannii and Klebsiella pneumoniae.  J Antimicrob Chemother. 2008 Sep;62 Suppl 1:i29-40.

Prasad Krishnan, Sudheer OV, Puneet Dhar, Sudhindran S, Shaji Ponnambathayil. Laparoscopy in suspected abdominal tuberculosis is useful as an early diagnostic method. ANZ Journal of Surgery 2008;78 (11):987-989.

Nair BT, Bhat SH, Narayan UV, Sukumar S, Saheed M, Kurien G, Sudhindran S.  Donate organs not malignancies: postoperative small cell lung carcinoma in a marginal living kidney donor. Transplant Proc. 2007 Dec;39(10):3477-80

Saheed MC, Sudhindran S, Bhat SH. Laparoscopic live-donor nephrectomy. BJU Int. 2006 Nov;98(5):1121-2

Sudhindran S, Sunil S, Sinha S. Platelet counts are persistently increased following simultaneous pancreas and kidney transplantation. Transplant Proc. 2006 Jun;38(5):1549-51

Surendran Sudhindran, Sanjay Bhat, K.V. Sanjeevan, C.S. Sayeed. Laparoscopic Right Donor Nephrectomy: Is There a Right Way? Journal of Endourology. 2006 May;20(5): 309-311

Saheed MC, Sudhindran S, Bhat SH. Laparoscopic live donor nephrectomy. BJU Int. 2006 Nov;98(5):1121-2.

Krishnan P, Chandrika K, Sudheer OV, Dhar P, Sudhindran S. Is sentinel node mapping useful in colorectal carcinoma? Indian J Gastroenterol. 2005 May-Jun;24(3):129-30.

V. Gandhi, V. Shyam, G. Unnikrishnan, D. Balakrishnan and S. Sudhindran. Ruptured Mycotic Aneurysm of Peroneal Artery. European Journal of Vascular and Endovascular Surgery 2005;10: 21–23 .

Unnikrishnan G, Dhar P, Sudhindran S. Chemoradiotherapy for rectal cancer. N Engl J Med 2005; 352:509-11; author reply 509-11.

Mehta RM, Sudheer VO, John AK, Sudhindran S, Dhar P. Spontaneous rupture of giant gastric stromal tumor into gastric lumen. World J Surg Oncol 2005; 3:11.

Mehta R, Unnikrishnan G, Sudheer OV, Sudhindran S, Dhar P. Incidental detection of tubular esophageal duplication in gastric cardia malignancy. Indian J Gastroenterol 2004; 23:192

S Sudhindran, KV Sanjeevan, CSM Sayeed, HS Bhat. Initial experience with Laparoscopic donor nephrectomies. Transplantation proceedings 2004 Sep;36(7):1901-2

KV Sanjeevan, HS Bhat, S Sudhindran. Laproscopic simultaneous bilateral pretransplant nephrectomyu for uncontrolled hypertension. Transplantation proceedings 2004 Sep;36(7):2011-2.

KV Sanjeevan, HS Bhat, S Sudhindran. Right sided Laparoscopic donor nephrectomy is feasible: experience with three cases. Transplantation Proceedings 2004 Sep;36(7):1907-8.

HS Bhat, KV Sanjeevan, S Sudhindran. Terminal hand assist for Laparoscopic donor nephrectomy. Transplantation Proceedings 2004 Sep;36(7):1905-6.

Taylor AL, Gibbs P, Sudhindran S, Key T, Goodman RS, Morgan CH, Watson CJ, Delriviere L, Alexander GJ, Jamieson NV, Bradley JA, Taylor CJ. Monitoring systemic donor lymphocyte macrochimerism to aid the diagnosis of graft-versus-host disease after liver transplantation. Transplantation. 2004 Feb 15;77(3):441-6.

Sudhindran S, Taylor A, Delriviere L, Collins VP, Liu L, Taylor  CJ, Alexander GJ, Gimson AE, Jamieson NV, Watson CJE, Gibbs P. Treatment of Graft-Versus-Host Disease After Liver Transplantation with Basiliximab Followed by Bowel Resection. American J Transplantation. 2003; 3(8): 1024-29.

Sudhindran S, Pettigrew GJ, Drain A, Shrotri M, Watson CJ, Jamieson NV, Bradley JA. Outcome of transplantation using kidneys from controlled (Maastricht category 3) non-heart-beating donors. Clin Transplant. 2003;17(2):93-100

Shrotri M, Sudhindran S, Gibbs P, Watson CJ, Alexander GJ, Gimson AE, Jamieson NV, Delriviere L. Case report of cavoportal hemitransposition for diffuse portal vein thrombosis in liver transplantation. Transplant Proc. 2003;35(1):397-8.

Shrotri M, Sudhindran S, Fernando BS, Pettigrew G, Watson CJ, Jamieson NV, Bradley JA. Revascularisation in transplant renal artery stenosis using the internal iliac artery. Transplant Proc. 2003 ;35(1):332-3.

Shrotri M, Fernando BS, Sudhindran S, Delriviere L, Watson CJ, Gibbs P, Alexander GJ, Gimson AE, Jamieson NV. Long-term outcome of liver transplantation for familial hypercholesterolemia. Transplant Proc. 2003;35(1):381-2

Sudhindran S, Taylor A. Shipped and locally transplanted renal allografts.
N Engl J Med  2002 ; 28:346(9):708-9

Waller JR, Richardson AC, Metcalfe MS, Sudhindran S et al. A multicentre analysis of the results of kidney transplantation from non-heart beating donors in the UK.  Br J Surg 2002; 89; s1,Transplant 04:7.

Sudhindran S, Bromwich E, Edwards PR. Prospective Randomised Double Blind Placebo Controlled Trial Of Glyceryl Trinitrate In ERCP Induced Pancreatitis. Br J Surg 2001; 88:1178 – 82.

Sudhindran S, Edwards PR. Surgical training takes time. Ann R Coll Surg Eng 2001; 83: 196-197

Gilling-Smith GL, Sudhindran S, Martin J, Brennan J, Gould D, McWilliams R, Bakran A, Harris PL. Freedom from endoleak after endovascular repair of abdominal aortic aneurysm does not equal treatment success. Eur J Vasc Surg 2000;19 (4):421- 425.

Sudhindran S, Rosser S, Pilbrow WJ, Sissons GRJ, de Cossart LM. The Impact Of Duplex Scanning For The Diagnosis Of Deep Vein Thrombosis On Workload In A District General Hospital.  Phlebology 1999; 14 ( 4):143-145.

Sudhindran S. Perioperative blood transfusion- a plea for guidelines. Ann R Coll Surg Eng. 1997; 79: 299 – 302.

Sudhindran S, Varghese CJ, Ramesh H. Pseudo myxoma peritonei- a retrospective analysis of eight cases. Ind J Gastroenterology 1994; 13(4): 137-9.

Sudhindran S, Bromwich E, Edwards PR. Double blind randomised controlled trial of buccal suscard versus placebo in the prevention of endoscopic retrograde cholangio pancreatography induced pancreatitis. Br J Surg 1998; 85 (suppl 2): 76 (abstract).

Ramesh H, Varghese CJ, Sudhindran S. Mortality following pancreaticoduodenectomy. Ind J Gastroenterology 1992; Vol. II (suppl): A50 M7

Reghu L, Sudhindran S, Jabbar. Acute intestinal obstruction due to sigmoid malignancy. Kerala Medical Journal 1992; 33(2): 48- 50.

Sudhindran S, Emms N, Sinha S, Kumar A. Too many confounding variables. Transplantation 2000;70: 1542 (letter).

Sudhindran S, Sinha S. Prospective study of primary anastamosis without colonic lavage for patients with obstructed colon. Br J Surg 2000; 87:376 (letter).

Sudhindran S. Reducing the risk of major elective surgery. Paper should have given details on causes of death. BMJ. 1999 Nov 20;319 (7221):1369A (letter).

S Sudhindran, Edwards PR, De Cossart LM. Mortality after elective abdominal aortic aneurysm; not where….but how many and by whom. Ann R Coll Surg Eng 1999; 81: 141-142.

Sudhindran S, Abbott GT, Edwards PR. Subclavian artery stenting for pseudoaneurysm. BMJ 1999. 318; 340 (Minerva).

Sudhindran S. Magnetic resonance imaging in evaluation of common bile duct stones. Br J Surg 1998; 85: 873 (letter).

Sudhindran S. An audit of hospital mortality after urgent and emergency surgery in the elderly. Ann R Coll Surg Eng. 1998; 80: 76 (letter).

Sudhindran S. Prospective randomized trial comparing sequential avulsion with stripping of the long saphenous vein. Br J Surg 1997; 84:727 (letter).

Sudhindran S. Vascular complications of injecting drug misuse. Br J Surg 1997; 84: 582-3 (letter)

Sudhindran S. Preoperative indicators to predict common bile duct stones. Am j Surg 1997; 173 (2): 150 (letter).

Sudhindran S, Reghunath KJ. Better bridge for loop stomas. Br J Surg 1996; 83: 1797 (letter).

Sudhindran S. Routine preoperative infusion cholangiography at elective cholecystectomy. Br J Surg 1996; 83: 1658 (letter).

Sudhindran S. Two layer closure of typhoid ileal perforations. Br J Surg 1996; 83: 282 (letter).

Sudhindran S. Blood transfusion requirements in femoral neck fractures. Ann R Coll Surg Eng 1996; 78: 156 (letter).

Research and Audit :

Co investigator for Qunintiles study protocol number 3074 A1- Randomised double blind study of Tigecycline versus Imipenem cilastatin for intraabdominal abcess.-Amrita Institute of Medical Sciences, Kochi.

Randomised controlled trial of early versus late removal of ureteric stents after living donor kidney translantation. A trial currently undergoing in Amrita Institute of Medical Sciences.

Non-heart beating donors for renal transplantation. Comparing the primary function rate, rejection rates and short term and long term graft survival rates between cadaveric hear beating and non heart berating donors for kidney transplantation in this unit, especially Category III non heart beating donors.

Graft versus Host disease after solid organ transplantation. Investigating the various clinical features, diagnostic methods and treatment options available for this rare but usually fatal complication after transplantation. The sensitivity, specificity and accuracy of method of assessment of peripheral chimerism for diagnosis of GVHD in this institute is being audited as well.

Platelet counts after Pancreatico renal transplantation.  A retrospective study focusing on blood platelet counts from patients with combined pancreatico-renal transplants (SPK), who were compared with Type I diabetic patients from the same era undergoing kidney only transplantation (KTA). Platelet counts from SPK has been found to be significantly raised when compared with KTA.

Surgical training times. Analysis of the time taken to perform various general surgical procedures between consultants and trainees from prospectively collected data at the Countess of Chester Hospital. Trainees were seen to take an average of 30% more time than consultants (published).

Double blind prospective randomised controlled trial of prophylactic buccal suscard in preventing ERCP induced pancreatitis. Trial done in Countess of Chester Hospital to assess the role of buccal suscard, a long acting nitrate (which relaxes the sphincter of Oddi) in reducing the incidence of post ERCP pancreatitis (published).

Analysis of EUROSTAR data pertaining to the use of Aortic Stents for abdominal aortic aneurysms, especially with respect to the significance of endoleaks and change in aortic aneurysm diameter (published).

Femoro-distal bypass grafting. Audit done in Aintree Hospitals Nhs Trust, Liverpool on the limb salvage and mortality rates of crural vessel bypasses for critical lower limb ischaemia.

30-day mortality and morbidity of carotid endarterectomy in a district general hospital. Retrospective Audit in Leighton hospital, Crewe.

Stay-in-rates after day case surgery. Retrospective Audit in Macclesfield District General Hospital.

Usage of Blood In General Surgery. Audit In Memorial Hospital, Darlington  pertaining to the large number of inappropriate transfusions used in general surgery (published).

A comparative study of various surgical techniques for Hydrocoele of the Tunica Vaginalis sac. Thesis submitted to the Kerala University as part of MS Degree in General Surgery.