• Kochi: (0) 484 2852100, 6682100, Faridabad: 0129-2851234

Dr. Shine Sadasivan

Clinical Professor

Department: Gastroenterology and Hepatology
Qualification: MD, DNB (Gastroenterology)
Email: shines1560@aims.amrita.edu

About Me

Achievements :

Poster On “Cost of Immunosupression using Generic Products After Liver Transplantation.”, Won the best poster Award at  International Liver Symposium in New Delhi, 2011.

Poster on “ Liver Transplantation – Moving Up the Learning curve” Won the Best Poster award at the Kerala chapter of the Association of Surgeon of India State Conference, Kochi, 2010.

Publications :

“Cost of Immunosupression using Generic Products After Liver Transplantation.”,      Journal of Clinical and Experimental Hepatology, Volume 1, Issue 2, (September 2011). ST Binoj, S Abubacker, R Menon, B Dinesh, G Unnikrishnan, OV Sudheer, P Dhar, S Sudhindran.

“Predictors For Need For  Liver Transplants In Acute Zinc Phosphide Poisoning”, Journal of Clinical and Experimental Hepatology, Volume 1, Issue 2, (September 2011). V Saraf, RK Suhas, U Dattaram, ST Binoj, R Menon, B Dinesh, G Unnikrishnan, OV Sudheer, S Sudhindran,P Dhar, N Subhalal.

“Bilirubin As A Predictor Of Early Mortality After Liver Transplantation.”,Journal of Clinical and Experimental Hepatology, Volume 1, Issue 2, (September 2011). S Kalghatgi, S Vivek, U Dattaram, ST Binoj, P Nitin, M Ramachandran, G Unnikrishnan, B Dinesh, OV Sudheer, D Puneet, N Subhalal, S Sudhindran.

Research Experience :

A Multinational, Multiceter, Randomized, Double Blinded Study comparing the Efficacy and Safety of Trial drug (AVE5026) with enoxaparin for the Prevention of Venous Thromboembolism in Patients Undergoing Abdominal Surgery, 2009-2010, Co-Investigator.

A Randomized, double blind, multicentric, placebo controlled, single dose, phase – II study assessing the safety and efficacy of intramuscular ex vivo cultured adult allogenic mesenchymal stem cells in patients with critical limb ischemia (CLI), , 2009-2011, Co-Investigator.

Neoadjuvant ChemoRT followed by surgery versus Neoadjuvant Chemo RT + Trial Drug Followed by surgery in Ca Esophagus. Prospective Multi centre Randomised Control Trial, 2008-2010. Co-investigator.

A Prospective, Multicenter, Double-blind, Randomized, Comparative Study to estimate the safety, tolerability and efficacy of Trial drug (NXL104)/Ceftazidime plus Metronidazole vs. Meropenem in the treatment of complicated intra-abdominal infections in hospitalized adults, 2009-2010, Co-Investigator.

A Phase III, Double Blind, Randomized Study to Evaluate the Safety and Efficacy of  Isavuconazole Versus Caspofungin Followed by Voriconazole Regimen in the Treatment of Candidemia and Other Invasive Candida Infections., 2009-2010, Co- investigator.

 Membership in Scientific Bodies :

Indian Medical Association.

Indian Association of Surgical Gastroenterologists.

Association of Surgeons of India.

Association of Minimal Access Surgeons of India.

About Me

Dr. Shines Sadasivan currently serves as Clinical Professor and Head in the Department of Gastroenterology and Hepatology at Amrita Institute of Medical Sciences. He obtained his MD in Internal Medicine from T.D Medical College, Alappuzha and DNB Gastroenterology from Amrita Institute of Medical Sciences, Kochi.

Area of interest

  • Liver diseases
  • GI Motility
  • Inflammatory Bowel disease


  1. Shine S, Raj VV, Dhar P, Narayanan VA, Nair P, Balakrishnan V. Clinico-colonoscopic differentiation of tuberculosis from Crohn’s disease. Proceedings of AGA. Gastroenterology, May 2005
  2. Colorectal cancer distribution in 220 Indian patients undergoing colonoscopy. Peedikayil MC, Nair P, Seena SM, Radhakrishnan L, Sadasivan S, Naryanan VA, Balakrishnan V. Indian J Gastroenterology. 2009 Dec;28(6):212-5. Epub 2010 Apr 28.
  3. Muscle cell membrane damage by very low serum sodium.,Varghese J, Balakrishnan V, Sadasivan S, Nair P, Narayanan VA. Pan Afr Med J. 2009 Nov 12;3:14.
  4. Fulminant hepatic failure for herpes simplex virus.Chatni SS, Sooraj V, Pande G, Sadasivan S, Narayanan VA, Balakrishnan V. J Indian Med Assoc. 2008 Jan;106(1):42, 44
  5. Acute myeloid leukemia presenting as obstructive jaundice.Rajesh G, Sadasivan S,Hiran KR, Nandakumar R, Balakrishnan V.Indian J Gastroenterol. 2006 Mar-Apr;25(2):934.
  6. Factors determining successful outcome following pneumatic balloon dilation in achalasia cardia.Mehta R, John A, Sadasivan S, Mustafa CP, Nandkumar R, Raj VV, Balakrishnan V.Indian J Gastroenterol. 2005 Nov-Dec;24(6):243-5.
  7. Skeletal infections in cirrhotics.Rajesh G, Mehta R, Nandakumar R, Sadasivan S, John A, Balakrishnan V.Indian J Gastroenterol. 2005 Jul-Aug;24(4):174-5.
  8. Infiltrating Strongyloides stercoralis presenting as duodenal obstruction.Suvarna D, Mehta R, Sadasivan S, Raj VV, Balakrishnan V.Indian J Gastroenterol. 2005 Jul-Aug;24(4):173-4.
  9. Natural course of asymptomatic pancreatic pseudocyst: a prospective study.Mehta R, Suvarna D, Sadasivan S, John A, Raj V, Nair P, Balakrishnan V.Indian J Gastroenterol. 2004 Jul-Aug;23(4):140-2.
  10. Rajiv Mehta, Deepak S, Anil John, Raj VV, Shine Sadasivan, Balakrishnan V. Takayasu’s arteritis presenting as chronic mesenteric ischaemia. Indian J Gastroenterol. 2004 March-April; 24(1): 6.
  11. Rajiv Mehta, Shine Sadasivan, Nandakumar R, Anil John, Narayanan VA, Puneet Dhar, Prem Nair, Balakrishnan V. Factors predicting successful outcome following first dose of neostigmine in acute colonic pseudoobstruction: a prospective study. Gastroenterology Proceeding of AGA, Gastroenterology, May 2005.
  12. Mehta Rajiv, Mustafa CP, Sadasivan S, John A, Raj VV, Narayanan VV, Balakrishnan V. Eosinophilic ascites. Indian J Surg 2005; 67: 227-228.
  13. Prognostic Value of Altered Liver Function Tests in Critically Ill Patients. Krishna Tejaswy · Harshavardhan Rao · Rajesh Gopalakrishna · Ismail Siyad · Shine Sadasivan · Harikumar Nair · Jeffey George · Anoop Koshy · Mathew Vadukoot · Rama Venu · V. Narayanan · Vallath Balakrishnan-Article · Jun 2015 · Journal of Clinical and Experimental Hepatology.
  14. Gastrointestinal: Abdominal wall metastasis after percutaneous endoscopic gastrostomy. S Chatni · A M Betigeri · S Sadasivan · P Nair · VA Narayanan · V Balakrishanan- Full-text · Article · Jul 2008 · Journal of Gastroenterology and Hepatology.
  15. Fulminant hepatic failure for herpes simplex virus Sanjeev S Chatni · V Sooraj · Gourav Pande · Shine Sadasivan · V A Narayanan · V Balakrishnan.
  16. G Rajesh · Ismail Siyad · Sreekanth Moorthy · V Sooraj · · zzz · Shine Sadasivan · V A Narayanan · Prem Nair · V Balakrishnan.
  17. Acute myeloid leukemia presenting as obstructive jaundice.
  18. G Rajesh · Shine Sadasivan · K R Hiran · R Nandakumar · V Balakrishnan.
  19. Factors determining successful outcome following pneumatic balloon dilation in achalasia cardia
  20. Rajiv Mehta · Anil John · Shine Sadasivan · C P Mustafa · R Nandkumar · V V Raj · V Balakrishnan.
  21. Splenic artery aneurysm with arteriovenous fistula as a cause of portal hypertension. M Rajiv · S Deepak · G Rajesh · Shine Sadasivan
  22. Indian consensus of chronic constipation in adults: A joint position statement of the indian motility and functional disease association and the Indian society of Gastroenterology. Indian journel of gastroenterology 2018; 37(6) 526-544 published online 2019 jan 8
  23. Comparison of Safety profile of ERCP in patients with cirrhotic and non – cirrhotic Portal Hypertension. Dr. Rama P Venu Dr. Shine Sadsivan
  24. Dr. Rajesh. G J. Clinical and Experimental Hepatology. July 2017;7:S91
  25. Correlation of insulin resistence with liver histology in obese patients with NASH and in lean NASH Dr. Shine Sadsivan Dr. Rajesh. G Journal of Clinical and Experimental Hepatology. Jul 2016 Volume 6
  26. Sushma Krishna, Shine Sadasivan, Kavitha Dinesh, Aswathy S, Shamsul Karim. From Colonoscope to Microscope: the Diagnosis of Trichuris Trichiura. International Journal of Case Reports, 2019 4:84.
  27. Rathod, P. & Dokhe, Yogesh & Jani, K. & Vidhyadharan, Sivakumar & Balasubramanian, Deepak & Iyer, Subramania & Thankappan, Krishnakumar & Sadasivan, Shine. (2019). PO-074 Pharyngoesophageal stricture following laryngeal-hypopharyngeal cancer treatment-management outcome. Radiotherapy and Oncology. 132. 38. 10.1016/S0167-8140(19)30240-3.
  28. Sarcoidosis, steroids and Strongyloides—what's the catch? A. Kumar ,R. Paulose,S. Sadasivan, C. Bajad, A. Ramachandran, P. Nair, published:September 17, 2020DOI:https://doi.org/10.1016/j.cmi.2020.09.012
  29. Thasneem.S, Yedu Krishnan SS, Dr.Shine Sadasivan, Roshni P R. A review on frailty in patient with liver cirrhosis and its management JCR. 2020; 7(17): 1790-1800. doi:10.31838/jcr.07.17.226
  30. Kannan Ayswarya, Biswas Lalitha, Kumar Anil, Kurian Jessy, S.Nair Anjaly, Suresh Parasmal et al . Improving Diagnosis of Hepatitis C Virus Infection Using Hepatitis C Core Antigen Testing in a Resource-Poor Setting. Rev. Soc. Bras. Med. Trop. [Internet]. 2021 [cited 2021 Mar 04] ; 54: e02532020. Available fromhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822021000100308&lng=en.EpubFeb10,2021. https://doi.org/10.1590/0037-8682-0253-2020.